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IPOL® is recommended for routine polio immunization
in the US1...
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An
adult traveler is considered fully immunized if he
or she has received a primary series of at least 3
doses of IPOL® before entry into a polioendemic
area1 |
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Is recommended by the American Academy of Pediatrics,
the Advisory Committee on Immunization Practices,
and the American Academy of Family Physicians2-4 |
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Has
been proven to confer herd
immunity against wild-type polio5-7 |
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Protects
against wild-type polio
without the risk of vaccine-associated paralytic polio
(VAPP) for patients and their contacts2,3 |
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Recommended
adult dosing
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2
doses administered at
intervals of 4 to 8 weeks |
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Third
dose administered
6 to 12 months after the second |
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Intramuscular administration |
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Accelerated
dosing for
time constraints1
| If
more than 8 weeks are available: |
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3
doses of IPV,*
4 weeks apart
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| If
4 to 8 weeks are available: |
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2
doses at least
4 weeks apart
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| If
less than 4 weeks: |
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a
single dose |
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*IPV= Inactivated Poliovirus Vaccine |
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Safety Information
IPOL® is indicated for the active immunization of infants,
children, and adults for the prevention of poliomyelitis.
Local adverse reactions may include fever, irritability,
drowsiness, anorexia, and crying. Other local and systemic
adverse reactions may occur. IPOL® is contraindicated
in persons with a hypersensitivity to any component of the
vaccine. As with any vaccine, vaccination with IPOL®
may not protect 100%
of susceptible individuals.
Click
here to view full Prescribing Information for IPOL®.
IPOL® is manufactured by Aventis Pasteur SA and distributed
by Aventis Pasteur Inc.
REFERENCES:
1. Centers for Disease and Control (CDC). Health
Information for International Travel 2001-2002. Atlanta,
GA: US Dept of Health and Human Services; 2001:131-133.
2. Recommendations of the Advisory Committee on Immunization
Practices: revised recommendations for routine poliomyelitis
vaccination. MMWR Morb Mortal Wkly Rep. 1999;48:590.
3. American Academy of Pediatrics: Committee on Infectious
Diseases. Prevention of poliomyelitis: recommendations for
use of only inactivated polio virus vaccine for routine
immunization. Pediatrics. 1999;104:1404-1406. 4.
American Academy of Pediatrics, Committee on Infectious
Diseases. Recommended childhood immunization scheduleUnited
States, 2002. Pediatrics. 2002;109:162-164. 5.
Strebel PM, Sutter RW, Cochi SL, et al. Epidemiology of
poliomyelitis in the United States one decade after the
last reported case of indigenous wild virus-associated disease.
Clin Infect Dis. 1992;14:568-579. 6. Plotkin
SA. Inactivated polio vaccine for the United States: a missed
vaccination opportunity. Pediatr Infect Dis J. 1995;14:835-840.
7. Salk D. Herd effect and virus eradication with
use of killed poliovirus vaccine. Dev Biol Stand.
1981;47:247-255.
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